Dr. David Sinclair is a professor at Harvard Medical School and the University of New South Wales, Sydney. He has been awarded the most prestigious prize in biological sciences by the Royal Swedish Academy for his work on age-related diseases. At 45 years old, Dr. Sinclair was the recipient of the 2013 Vance Stephen Memorial Award from The Endocrine Society.
Dr. Sinclair has made significant discoveries in the fields of aging and age-related diseases. His work has found links between resveratrol and sirtuins, proteins with anti-aging properties in mice, and in human beings too.
The Sinclair Lab at Harvard Medical School is looking for ways to prevent or reverse neurodegenerative diseases and cancer. Through genetic manipulations of mitochondrial DNA, Dr. Sinclair found that aging can be reversed in mice. Upon inducing the expression of certain proteins guarded by mitochondria, he managed to make them younger and healthier.
Additionally, with a team of his students and postdoctoral fellows at Harvard Medical School, Sinclair found a way to convert skin cells from old humans into embryonic-like stem cells that have the ability to become any type of cell in the body. This finding has been hailed as a potential cure for many diseases including Parkinson’s disease, Huntingtons Disease and Alzheimer’s disease.
In 2014, Sinclair was appointed as a Professor at the University of New South Wales, Sydney. There, he will continue his work on reversing the aging process and curing age-related diseases.
Sinclair has said that “the main focus of my lab is to find interventions that can prevent or reverse neurodegenerative diseases and cancer. We are particularly interested in understanding how mitochondrial DNA mutations drive these diseases, and then using this information to develop novel therapies.”
Dr. David Sinclair is a highly accomplished and renowned scientist who has made significant contributions to the fields of aging and age-related diseases. He is a professor at Harvard Medical School and the University of New South Wales, Sydney, and has been awarded many prestigious prizes for his work in these areas.